Br J Anaesth 1997; 78: 247–55, Tramèr M, Moore A, McQuay H: Meta-analytic comparison of prophylactic antiemetic efficacy for postoperative nausea and vomiting: propofol anaesthesia vs omitting nitrous oxide vs a total i.v. NIH The same argument applies for nonsmokers who are more likely to develop the complications than smokers: nausea (OR = 2.41; 1.26–4.60) and vomiting (OR = 3.0; 1.35–6.71). Gan, T. J., et al. Please enable it to take advantage of the complete set of features! This is in accordance with the results of a meta-analysis performed by Tramèr et al. Anaesthesia 2000; 55: 540–4, Junger A, Hartmann B, Benson M, Schindler E, Dietrich G, Jost A, Béye-Basse A, Hempelmann G: The use of an anesthesia information management system for prediction of antiemetic rescue treatment at the postanesthesia care unit. Search for other works by this author on: Watcha MF, White PF: Postoperative nausea and vomiting: Its etiology, treatment, and prevention. POSTOPERATIVE nausea and vomiting—usually summarized as PONV—remains one of the most common and distressing complications after surgery. This literature shows that female gender post-puberty, nonsmoking status, history of PONV or motion sickness, childhood after infancy and younger adulthood, increasing duration of surgery, and use of volatile anesthetics, nitrous oxide, large-dose neostigmine, or intraoperative or postoperative opioids are well established PONV risk factors. The survey was performed in a clinical audit setting. Our study gave detailed information on the time course of postoperative nausea and vomiting. INTRODUCTION. Background: /st> In assessing a patient's risk for postoperative nausea and vomiting (PONV), it is important to know which risk factors are independent predictors, and which factors are not relevant … Introduction Postoperative nausea and vomiting (PONV) are disabling symptoms after surgery. Possible risk factors include history of migraine, history of PONV or motion sickness in a child's parent or sibling, better ASA physical status, intense preoperative anxiety, certain ethnicities or surgery types, … [Article in English, Spanish] Veiga-Gil L(1), Pueyo J(2), López-Olaondo L(2). Upon arrival in the postanesthesia care unit, patients were asked by the nurse to rate their nausea experience on the VAS device. A P  value < 0.05 was considered significant. Eur J Anaesth 1992; 9(suppl 6): 25–31, Andrews PLR: Towards an understanding of the mechanism of PONV, The Effective Management of Postoperative Nausea and Vomiting. Recommendations for prevention and treatment, and research agenda. Among perioperative related factors, general anesthesia influenced the probability of nausea and vomiting, but there was no direct association between the duration of anesthesia and the incidence of PONV, as demonstrated by Sinclair et al. There was a clear relationship between nausea and vomiting. Although risk factors for postoperative nausea are generally assumed as being the same as those for vomiting, the present study made a clear distinction between the two events, considered as two different end points. Nevertheless, this study included 46% of children and focused only on patients after specific surgical procedures, i.e. Br J Anaesth 2002; 88: 234–40, Bardiau FM, Braeckman MM, Seidel L, Albert A, Boogaerts JG: Effectiveness of an acute pain service inception in a general hospital. Overall, however, the type of surgery was significantly associated with nausea but not with vomiting, except for urological procedures (P = 0.037). The inhalational agents are variably associated with postoperative nausea and vomiting, and nitrous oxide … Among the 126 patients with nausea, 53 (42%) experienced vomiting. 6,8However, review of the literature on individual factors contributing to PONV is often complicated by the lack of standardization in the definitions of “nausea,”“retching,” and “vomiting.” The interchangeable use of the terms nausea and vomiting has led to much confusion because the symptoms do not always accompany each other in severity. , in day-case surgery. 4Data concerning nausea and vomiting were registered on the patient's case report form. 28Results of our study are unable to support this statement. Several risk factors are incriminated in their occurrence. 6and Koivuranta et al. In the present study, patients without and with nausea or vomiting received a similar amount of sufentanil throughout the operative procedure. 29Review of the literature on anesthetic factors contributing to PONV is difficult because of a lack of standardization. Results of the Application of the Bivariate Dale Model to Nausea and Vomiting Data. It is commonly stated that risk factors for postoperative nausea are the same as for vomiting. Our goal is to determine the incidence of postoperative nausea and vomiting … Apfel, C. C., et al. Time-related pain VAS measurements were summarized by various parameters as described elsewhere: AUC = area under the VAS–time curve (cm × h); mean VAS (cm); VASmax = peak of VAS (cm); Tmax = time of VASmax (h); and PVAS > 3 = the persistence of pain VAS over 3 cm, i.e. Surgical factors that confer increased risk for PONV include procedures of increased length, gynecological, … The present epidemiologic study was designed to discern risk factors of PONV with a clear distinction between the two events. Possible risk factors include history of migraine, history of PONV or motion sickness in a child's parent or sibling, better ASA physical status, intense preoperative anxiety, certain ethnicities or surgery types, decreased perioperative fluids, crystalloid versus colloid administration, increasing duration of anesthesia, general versus regional anesthesia or sedation, balanced versus total IV anesthesia, and use of longer-acting versus shorter-acting opioids. Patients were excluded if they were unable to understand or realize a visual analog scale (VAS) test, were transferred directly to an intensive care unit, were undergoing an emergency procedure, had preexisting nausea or vomiting, or had received drugs with antiemetic properties 4 h before surgery. Yingjie Wang Department of Orthopedic Surgery, Peking Union Medical College … [Risk factors and frequency of postoperative nausea and vomiting in patients operated under general anesthesia]. Among the patients, 480 (72%) received general anesthesia, and 191 (28%) received locoregional anesthesia. Pharmacologic reversal of neuromuscular blocking agents was administered in 19 patients (4%) using neostigmine methylsulfate at a mean dose of 1.5 mg associated with glycopyrrolate (mean dose, 0.4 mg) or atropine (mean dose, 0.3 mg). 3,6,8,11Indeed, we found that some risk factors were predictive of both nausea and vomiting (female gender, nonsmoking status, general anesthesia) but that history of migraine and type of surgery, with the exception of urology, were solely related to nausea. 15These measurements are in accordance with the studies conducted by Cohen et al. It is also possible to test whether the association is dependent on the covariates. 3,6,8,11 Indeed, we found that some risk factors were predictive of both nausea and vomiting (female gender, nonsmoking status, general anesthesia) … Grabowska-Gaweł A, Porzych K, Piskunowicz G. J Oral Maxillofac Surg. 15No special instructions were given to the attending anesthesiologist regarding anesthesia and postoperative analgesia regimens. There are a number of risk factors for PONV. The incidence of PONV after administration of various anesthetic agents reported by different authors cannot be compared since each group of authors used different criteria and different population groups. Undesirable Postoperative Anesthesia Outcomes at Two National Referral Hospitals: A Cross-Sectional Study in Eritrea. All drugs given for pain relief were documented. Patient-, anesthesia-, and surgery-related variables that were considered to have a possible effect on the proportion of patients experiencing postoperative nausea and/or vomiting were examined. Recently, Apfel et al. Acta Anaesthesiol Scand 2001; 45: 4–13, Kamath B, Curran J, Hawkey C, Beattie A, Gorbutt N, Guiblin H, Kong A: Anaesthesia, movement and emesis. History of migraine and type of surgery were mainly responsible for nausea but not for vomiting. BMC Anesthesiol. Anesthesiol Res Pract. Patients undergoing general anesthesia have an increased risk of nausea (OR = 2.51; 1.10–5.72) and of vomiting (OR = 3.67; 1.25–10.8) when compared to patients undergoing locoregional anesthesia. 2014. , 23Apfel et al. In turn, the most complicated model incorporates all covariates for both outcomes. , 26,27who found that intravenous induction of anesthesia with propofol has no relevant effect on PONV. Postoperative incidence rates of nausea and vomiting were estimated from the data. Meng, … BMC Anesthesiol. Results were considered to be significant at the 5% critical level (P < 0.05). Comparison of the Effects of Sugammadex, Neostigmine, and Pyridostigmine on Postoperative Nausea and Vomiting: A Propensity Matched Study of Five Hospitals. To identify among preoperative and perioperative risk factors those predictive of postoperative nausea and vomiting, we fitted the bivariate Dale model to the data set by including all covariates, namely, gender, age, BMI, nonsmoking status, history of migraine and of PONV, type of anesthesia, and duration and type of surgery (using ENT as the reference group). 2020 Nov 18;20(1):288. doi: 10.1186/s12871-020-01205-5. Anesth Analg 1994; 78: 7–16, Palazzo M, Evans R: Logistic regression analysis of fixed patient factors for postoperative sickness: A model for risk assessment. Factors related to postoperative nausea and vomiting. Risk factors of postoperative nausea and vomiting after total hip arthroplasty or total knee arthroplasty: a retrospective study. , droperidol, or more antiemetic efficacy, i.e. The overall incidence of nausea was 19%, and that of vomiting was 10%. There are so many other factors (like anesthesia, pain medication, and patient issues) that can lead to PONV that it is assumed that any surgery is a risk for postoperative nausea and vomiting. The authors thank Professor Geert Molenberghs, Ph.D. (Department of Biostatistics, Limburgs Universitair Centrum, Diepenbeek, Belgium), for helpful discussions and advice on the Dale model. AUC = area under the curve; BMI = body mass index; NSAID = nonsteroidal antiinflammatory drug; PONV = postoperative nausea and vomiting; PVAS = persistence of VAS pain scores; VAS = visual analog scale; T max = time of the maximal pain score. 32–34Nausea is a subjective sensation requiring activation of neural pathways, which eventually project to areas of the cerebral hemispheres dealing with conscious sensations. Both nausea and vomiting. are in accordance with the survey performed by et. 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